Usefulness of drug provocation tests in children with a history of adverse drug reaction
نویسندگان
چکیده
منابع مشابه
Usefulness of drug provocation tests in children with a history of adverse drug reaction
PURPOSE There are very few reports of adverse drug reactions (ADR) and almost no study of drug provocation test (DPT) in Korean children. We aimed to assess the role of DPT in children with unpredictable ADRs, and compare the causative drugs and clinical characteristics between detailed history of ADRs and result of DPTs. METHODS We included 16 children who were experienced ADRs referred to p...
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Almost two-thirds of patients who visit a doctor for a reaction that is diagnosed as a ‘drug allergy’ (DA) are not allergic. This false claims of drug allergy leads to unnecessary avoidance of fi rst choice drugs, exposes the patient to less effective and potentially more toxic drugs, increases healthcare costs, and contributes to the development of antibiotic resistance. Therefore, a drug alle...
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Skin testing with the suspected drugs may be helpful in determining the cause of a cutaneous adverse reaction (CADR). Tetrazepam (T) is a muscle relaxant of the benzodiazepine group frequently used in rheumatology in association with anti-inflammatory drugs (AIDs). We propose to determine the usefulness of patch testing in this context. Patients and methods A retrospective study was conducted i...
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BACKGROUND Adverse drug reactions (ADRs) are a common healthcare problem. The drug provocation test (DPT) is a gold standard for ADR diagnosis. OBJECTIVES To evaluate a correlation between history of ADRs, skin prick test (SPT), intradermal test (ID) and DPT in Thai children. METHODS This was a retrospective review of 211 children under 16 years of age who had a history of ADRs and underwen...
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Drug provocation tests in children are always a problematic task. In the present article the most important aspects of this technique are reviewed, including the differences between children and adults; the main mechanisms involved in drug reaction; how to perform the different tests; and when they are indicated.
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ژورنال
عنوان ژورنال: Korean Journal of Pediatrics
سال: 2011
ISSN: 1738-1061
DOI: 10.3345/kjp.2011.54.7.304